24 de febrero de 2021
ÚLTIMAS NOTICIAS:
 1300x90
Hispanic World

Brazil finds factor upping chance of being infected with UK virus strain

Rio de Janeiro, Jan 5 (efe-epa).- A group of Brazilian researchers has identified one of the factors that increases the possibility of infection by the British strain of the coronavirus, which is some 70 percent more infectious than other variants, the Foundation for Support of Research in Sao Paulo State (Fapesp).

 In an announcement made on Jan. 5, 2021, Brazilian researchers said they had determined that the protein spike of the new British strain of the coronavirus has greater molecular interactive strength with the ACE2 receptor, which is present on the surface of human cells and with which the SARS-CoV-2 virus connects to begin the process of infection, thus making this new strain up to 70 percent more contagious than the original virus strain identified in Wuhan, China. EFE-EPA/Sebastiao Moreira/File

In an announcement made on Jan. 5, 2021, Brazilian researchers said they had determined that the protein spike of the new British strain of the coronavirus has greater molecular interactive strength with the ACE2 receptor, which is present on the surface of human cells and with which the SARS-CoV-2 virus connects to begin the process of infection, thus making this new strain up to 70 percent more contagious than the original virus strain identified in Wuhan, China. EFE-EPA/Sebastiao Moreira/File

Rio de Janeiro, Jan 5 (efe-epa).- A group of Brazilian researchers has identified one of the factors that increases the possibility of infection by the British strain of the coronavirus, which is some 70 percent more infectious than other variants, the Foundation for Support of Research in Sao Paulo State (Fapesp).

The Brazilian researchers determined that the protein spike of the new strain, which is what forms the structure of the virus's corona that gives the name to the coronavirus family, has greater molecular interactive strength with the ACE2 receptor, which is present on the surface of human cells and with which the SARS-CoV-2 virus connects to begin the process of infection.

"The increase in the strength of the molecular interaction of the new line is caused by a mutation already identified in amino acid 501 of the SARS-CoV-2 protein spike called N501Y, which gave the start to the new variant of the virus," said Fapesp in a statement published on its Website.

The discovery was made by researchers at the University of Sao Paulo (USP) in a study financed by Fapesp and whose results were published on Tuesday on the bioRxiv international scientific web page in an article that has not yet been reviewed by other scientists.

The so-called British variant, dubbed B.1.1.7, has already been detected in some 20 countries - including two cases in Brazil - and is distinguished by a mutation that affects the way in which the virus affixes itself to human cells, something that makes it much more contagious than the earlier versions of the virus.

"We determined that the interaction between the protein spike of the new strain with the N501Y mutation is much greater than that presented by the first kind of the virus that was isolated in Wuhan (China)," said Geraldo Aleixo Passos, a USP researcher and one of the leaders of the study.

"There are other mutations in the genome of the new line that we're not analyzing. We're focusing on N501Y because it's implicated in connection with the protein spike with ACE2," he added.

To confirm their hypothesis, the research team performed tests with structures of the protein spike of the Wuhan coronavirus and with the new British strain, along with analysis using PyMOL public domain software.

"The results of the analyses showed that the mutation in the protein of the new variant establishes a greater interaction with the ACE2 receptor compared to the strain isolated in Wuhan," Fapesp said.

"Adding the various weak connections between the mutant protein spike with the human ACE2 receptor resulted in stronger molecular interactions, which allow the virus to more easily penetrate the cells and trigger the replication system," Passos said.

Despite having sparked alarm in the UK due to its high contagion rate, so far there is no evidence that the British strain results in more serious Covid-19 cases than the original strain, has a greater mortality rate or is resistant to the existing anti-Covid vaccines.

Brazil, one of the countries hardest hit by the pandemic, last week detected its first two cases of the British viral strain.

The South American giant has suffered the second-highest number of deaths from Covid-19 so far - about 200,000 - after the United States, and is in third place in terms of its caseload with almost 7.8 million confirmed cases, following the US and India.

Histórico de noticias
Miami's Virginia Key, a beach symbol of civil rights struggle

Miami, Feb 24 (efe-epa).- A beach in Miami stands as a symbol of the fight for civil rights. Virginia Beach in August 1945 was designated for the use of...

Tiger Woods seriously injured in one-car rollover crash near Los Angeles

Los Angeles, Feb 23 (efe-epa).- Golf icon Tiger Woods, who on Tuesday morning was injured in a one-car rollover crash in Los Angeles County, California, is...

Perez: Fraud, 16K inconsistencies in Ecuador presidential vote

Quito, Feb 23 (efe-epa).- Indigenous presidential candidate Yaku Perez said Tuesday that "more than 16,000 records with inconsistencies" have been detected...

Senate examines colossal security breakdown surrounding Capitol attack

Washington, Feb 23 (efe-epa).- The US Senate on Tuesday examined the "colossal" security breakdown that enabled angry supporters of then-President Donald...

NASA releases 1st video, audio of Perseverance landing on Mars

Miami, Feb 22 (efe-epa).- NASA on Monday released the first video of the landing of the Perseverance exploratory probe on Mars and also the first sounds...

Huawei vice president calls for global consensus on technological development

Mexico City, Feb 22 (efe-epa) - Latin America's challenge in improving Internet connectivity in rural and urban areas to reduce the digital divide, which is...

Supreme Court rejects Trump's attempt to keep tax returns hidden

Washington, Feb 22 (efe-epa).- The US Supreme Court on Monday rejected former President Donald Trump's refusal to turn over some of his tax returns to the...

If you want to forget about Covid-19, visit Haiti

Port-au-Prince, Feb 21 (efe-epa).- A year into the coronavirus pandemic, it is impossible to get away from the constant inflow of information about Covid-19...

US formally offers to restart talks with Iran, Washington media report

Washington, Feb 18 (efe-epa).- The Joe Biden administration has formally offered to restart nuclear talks with Iran, according to US media reports on...

Kamala Harris's stepdaughter makes debut as model in New York

New York, Feb 18 (efe-epa).- Ella Emhoff, the stepdaughter of US Vice President Kamala Harris, on Thursday made her debut as a model during New York Fashion...

Perseverance robot rover touches down safely on Martian surface

Miami, Feb 18 (efe-epa).- The Perseverance space probe has landed safely on Mars after successfully passing through the expected "seven minutes of terror"...

Mexico out front in pressuring UN to guarantee anti-Covid vaccine access

By Cristina Sanchez Reyes

Maduro: I had lots of contacts with Trump administration

Caracas, Feb 17 (efe-epa).- Venezuelan President Nicolas Maduro said Wednesday that his government had "heaps of contacts" with the Donald Trump...

Argentine kids return to class after almost a year of remote learning

By Rodrigo Garcia Melero

Former Trump casino demolished

New York, Feb 17 (efe-epa).- Atlantic City's Trump Plaza Hotel and Casino, which welcomed the rich and famous for years, on Wednesday was demolished in a...

An order of tuna sashimi, please. Have the robot bring it to me!

By Marc Arcas

Brazil wraps up odd Carnival without samba but with clandestine parties

Rio de Janeiro, Feb 16 (efe-epa).- Brazil on Tuesday is wrapping up this year's Carnival, an unusual celebration given the lack of samba school parades, the...

Pelosi: Commission similar to 9/11 entity to investigate Capitol attack

Washington, Feb 15 (efe-epa).- Speaker of the House Nancy Pelosi announced Monday the creation of an independent commission that will examine the "facts and...

Biden prioritizes rescuing economy, fighting pandemic after impeachment

Washington, Feb 15 (efe-epa).- With the impeachment proceedings against former President Donald Trump now over, President Joe Biden is focusing on pushing...

Mexican president calls for urgent UN meeting over vaccine hoarding

Mexico City, Feb 15 (efe-epa).- Mexican President Andres Manuel Lopez Obrador said Monday that the United Nations should convene an "urgent meeting" to deal...

Trump holds onto GOP reins, wants to make senators voting to convict pay

By Beatriz Pascual Macias

Argentine president decrees 3 days of mourning for Menem

Buenos Aires, Feb 14 (efe-epa).- Argentine President Alberto Fernandez on Sunday expressed his "deep sorrow" over the death, and his "respect for (the)...

Impeachment managers: If Trump is acquitted he could foment violence again

Washington, Feb 11 (efe-epa).- Democratic congresspeople acting as the "managers" of ex-President Donald Trump's second impeachment trial on Thursday sought...

New York mayoral race attracting some 30 candidates

By Jorge Fuentelsaz